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Callosum raises $100M to build an alternative to winner-takes-all in AI

Resilience and digital sovereignty goals bring a wave of partners, mega VCs and the UK government into seed round

Ingrid LundenbyIngrid Lunden
August 20, 2026
in News, Startups
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Neural networks, a model for building computing that mimics what we understand about how the brain works, has long been one of the key concepts to underpin the development of artificial intelligence. Now, a new UK startup called Callosum has raised a seed round of $100 million to apply neural concepts to how computing infrastructure is built and operates.

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The goal: to make AI, and other applications that require heavy compute workloads, more efficient — faster, cheaper to run, and less energy- and chip-intensive — than they are today by creating an integration platform that lets multiple vendors work together to power compute and models.

It’s announcing the funding with a long list of secured partners, including chip companies Rebellions, Cerebras, Axelera AI alongside NVIDIA, AMD and Intel; the server company Supermicro; integration specialist Normal Computing; cloud giant AWS; Furiosa and many more.

Callosum’s aim may be to reduce costs and be more efficient, but that effort will clearly require a big investment of its own. A $100 million seed round is one of the largest ever for a startup in Europe and speaks to what it might need to raise in subsequent rounds.

If the funding amount and partners don’t already spell out some of the startup’s ambitions, its investor list is also very eye-catching and underscores how heated the market is right now, not just for AI but what comes next, since the AI industry feels like an untenable bubble with high operation costs that are being carried by investor money, not profit.

The seed round is led by Atomico, one of the biggest VCs in Europe; others in the round with “significant participation” include Plural, the London-based VC that has carved out a reputation for itself in defence, sovereign and resilience technologies; the US investor DCVC. The UK Sovereign AI Fund is also a major investor, and that is also a big deal. It’s the government organisation’s first named investment after announcing a £500 million fund to invest in more independent, sovereign UK AI computing operations earlier this year.

Callosum is co-founded by Danyal Akarca and Jascha Achterberg, neuroscience researchers who met while working on their PhDs at Cambridge University, and it’s already hired a bunch of people from across the industry and academia for its initial push.

We are due to speak with Achterberg later and will update this post with more then. For now, here is a rundown on what Callosum is doing, and why it will have caught the eye of investors and others in the industry; and why it matters in the context of “resilience tech” and digital sovereignty:

First of all, Callosum describes its core concept as “heterogeneous”.

This is not only a reference to how brains work when they fire many circuits and neurons to learn, remember, and apply learnings in real time. It is also a reference to how Callosum believes computing infrastructure should be built. AI works best and most efficiently, they argue, when multiple operators, in the form of chips and data centres and AI and other models, work in concert rather than individually.

This, as it turns out, touches on some elusive goals in the world of AI in particular around diversification and efficiency.

There are a number of companies competing across chips, foundational models, data centres, and other aspects of the ecosystem, but in that mix, there are some outsized companies that control the market. Nvidia dominates the processing space; Anthropic and OpenAI are pulling in huge numbers of users and funding and data that all help them build even more powerful models, and so on.

You can see how this would appeal to different stakeholders.

Vendors don’t want Nvidia to be the only name synonymous with processing. Users want more choice and thus lower costs in the software and hardware they buy. And investors want to make sure that their AI investments also have a fighting chance of success longer-term, and they want to find more, not less, founders innovating and building more technology.

Callosum’s concept gives potential space for multiple companies across the ecosystem to play a part and have specialised uses and users. (It calls this “tailored inference”, in opposition to what it describes аs standardised solutions.)

And if it can pull off building a genuinely useful integration layer, Callosum has a potentially important role to play as a platform provider — a holy grail in tech for companies that hope to stick around for the long haul.

Callosum already has a product page up on its site where it is inviting interested parties — potential customers who want to take compute, and vendors who want to be a part of its platform — to get in touch, although it’s not clear if it’s yet commercially launched.

There is a big opportunity here to play into not just more widely how AI and other resource-intensive compute develops, but specifically how it develops outside of the countries that are the biggest in AI today.

One big question that has hovered over countries in Europe and other regions outside of the US and China is how their own nations can develop systems that are truly independent rather than interdependent, in order to improve their own sovereignty in critical moments.

The UK may be doubling down on working with US-based technology companies, but even in times of peace, the US has shown that it is capable of dictating how those companies operate; and that’s before considering how the UK interfaces with countries that are more clearly adversarial.

It’s no surprise that the UK’s Sovereign AI fund is interested in Callosum. Backing a UK startup that’s building a platform that might offer a route for building systems that can be more flexible, with components that could be swapped in and out more easily too, could be one way to offset the lack of home-grown technology within the country using it.

“When workloads can move fluidly across many models and many chips, no single vendor holds a chokepoint over anyone’s access to intelligence,” notes Atomico. “Resilient access to intelligence is fast becoming a matter of national sovereignty, which is why governments and enterprises can’t afford to wait.”

Tags: callosum
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GALLOS Technologies raises £35M to expand defence tech portfolio

Ingrid Lunden

Ingrid Lunden

Ingrid is an editor and writer. Born in Moscow, brought up in the U.S. and now based out of London, from February 2012 to May 2025, she worked at leading technology publication TechCrunch, initially as a writer and eventually as one of TechCrunch’s managing editors, leading the company’s international editorial operation and working as part of TechCrunch’s senior leadership team. She speaks Russian, French and Spanish and takes a keen interest in the intersection of technology with geopolitics.

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